2. Signaling Pathways
  3. GPCR/G Protein
    Immunology/Inflammation
    Neuronal Signaling
  4. Histamine Receptor
  5. Histamine Receptor Activator

Histamine Receptor Activator

Histamine Receptor Isoform Comparison

Histamine Receptor Activators (6):

Cat. No. Product Name Effect Purity
  • HY-B1204S
    Histamine-α,α,β,β-d4 dihydrochloride
    		Activator 99.71%
    Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
  • HY-101225
    8 Hydroxy PIPAT oxalate
    		Activator
    8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that promotes the release of histamine from enteric mast cells. 8 Hydroxy PIPAT oxalate activates serotonergic signaling pathways, leading to the degranulation of mast cells in both guinea pig and human intestinal preparations. 8 Hydroxy PIPAT oxalate enhances the spontaneous release of histamine, which may contribute to the regulation of gastrointestinal functions. 8 Hydroxy PIPAT oxalate has potential implications for understanding and treating functional gastrointestinal disorders such as irritable bowel syndrome.
  • HY-N19243
    6-O-Senesioyl plenolin
    		Activator
    6-O-Senesioyl plenolin is a sesquiterpene lactone found in Centipeda minima with antiallergic activity. 6-O-Senesioyl plenolin inhibits histamine release from mast cells (IC50 = 18 μM) and suppresses pigment exudation in passive cutaneous anaphylaxis tests. 6-O-Senesioyl plenolin can be used in research related to allergy.
  • HY-158297
    Histamine/OVA
    		Activator
    Histamine/OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
  • HY-178350
    MFDCH016
    		Activator
    MFDCH016 is a potent HDAC1/6 (IC50 = 38/59 nM) and CDK4/6 (IC50 = 680/720 nM) inhibitor. MFDCH016 induces apoptosis and cell cycle arrest in G2/M and G0/G1 phases in MCF-7 cells. MFDCH016 can modulate the HDAC-p21-CDK signaling pathway, increasing the levels of acetylated H3 and p21. MFDCH016 can be used for the study of breast cancer.
  • HY-107063
    AHR-1911
    		Activator 99.66%
    AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis.